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Association of immediate versus delayed extubation of patients admitted to intensive care units postoperatively and outcomes: A retrospective study

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  • Paul Zajic
  • Michael Eichinger
  • Michael Eichlseder
  • Barbara Hallmann
  • Gabriel Honnef
  • Tobias Fellinger
  • Barbara Metnitz
  • Martin Posch
  • Martin Rief
  • Philipp G H Metnitz

Abstract

Aim of this study: This study seeks to investigate, whether extubation of tracheally intubated patients admitted to intensive care units (ICU) postoperatively either immediately at the day of admission (day 1) or delayed at the first postoperative day (day 2) is associated with differences in outcomes. Materials and methods: We performed a retrospective analysis of data from an Austrian ICU registry. Adult patients admitted between January 1st, 2012 and December 31st, 2019 following elective and emergency surgery, who were intubated at the day 1 and were extubated at day 1 or day 2, were included. We performed logistic regression analyses for in-hospital mortality and over-sedation or agitation following extubation. Results: 52 982 patients constituted the main study population. 1 231 (3.3%) patients extubated at day 1 and 958 (5.9%) at day 2 died in hospital, 464 (1.3%) patients extubated at day 1 and 613 (3.8%) at day 2 demonstrated agitation or over-sedation after extubation during ICU stay; OR (95% CI) for in-hospital mortality were OR 1.17 (1.01–1.35, p = 0.031) and OR 2.15 (1.75–2.65, p

Suggested Citation

  • Paul Zajic & Michael Eichinger & Michael Eichlseder & Barbara Hallmann & Gabriel Honnef & Tobias Fellinger & Barbara Metnitz & Martin Posch & Martin Rief & Philipp G H Metnitz, 2023. "Association of immediate versus delayed extubation of patients admitted to intensive care units postoperatively and outcomes: A retrospective study," PLOS ONE, Public Library of Science, vol. 18(1), pages 1-13, January.
    • Handle: RePEc:plo:pone00:0280820
    DOI: 10.1371/journal.pone.0280820
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