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Prognostic factors for favorable outcomes after veno-venous extracorporeal membrane oxygenation in critical care patients with COVID-19

Author

Listed:
  • Bärbel Kieninger
  • Magdalena Kilger
  • Maik Foltan
  • Michael Gruber
  • Dirk Lunz
  • Thomas Dienemann
  • Stephan Schmid
  • Bernhard Graf
  • Clemens Wiest
  • Matthias Lubnow
  • Thomas Müller
  • Bernd Salzberger
  • Wulf Schneider-Brachert
  • Martin Kieninger

Abstract

Background: Patients with COVID-19 and severe acute respiratory failure may require veno-venous extracorporeal membrane oxygenation (VV ECMO). Yet, this procedure is resource-intensive and high mortality rates have been reported. Thus, predictors for identifying patients who will benefit from VV ECMO would be helpful. Methods: This retrospective study included 129 patients with COVID-19 and severe acute respiratory failure, who had received VV ECMO at the University Medical Center Regensburg, Germany, between 1 March 2020 and 31 December 2021. Patient-specific factors and relevant intensive-care parameters at the time of the decision to start VV ECMO were investigated regarding their value as predictors of patient survival. In addition, the intensive-care course of the first 10 days of VV ECMO was compared between survivors and patients who had died in the intensive care unit. Results: The most important parameters for predicting outcome were patient age and platelet count, which differed significantly between survivors and non-survivors (age: 52.6±8.1 vs. 57.4±10.1 years, p

Suggested Citation

  • Bärbel Kieninger & Magdalena Kilger & Maik Foltan & Michael Gruber & Dirk Lunz & Thomas Dienemann & Stephan Schmid & Bernhard Graf & Clemens Wiest & Matthias Lubnow & Thomas Müller & Bernd Salzberger , 2023. "Prognostic factors for favorable outcomes after veno-venous extracorporeal membrane oxygenation in critical care patients with COVID-19," PLOS ONE, Public Library of Science, vol. 18(1), pages 1-15, January.
    • Handle: RePEc:plo:pone00:0280502
    DOI: 10.1371/journal.pone.0280502
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