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Particulate matter 2.5, metropolitan status, and heart failure outcomes in US counties: A nationwide ecologic analysis

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  • Edward W Chen
  • Khansa Ahmad
  • Sebhat Erqou
  • Wen-Chih Wu

Abstract

The relationship between particulate matter with a diameter of 2.5 micrometers or less (PM2.5) and heart failure (HF) hospitalizations and mortality in the US is unclear. Prior studies are limited to studying the effects of daily PM2.5 exposure on HF hospitalizations in specific geographic regions. Because PM2.5 can vary by geography, this study examines the effects of annual ambient PM2.5 exposure on HF hospitalizations and mortality at a county-level across the US. A cross-sectional analysis of county-level ambient PM2.5 concentration, HF hospitalizations, and HF mortality across 3135 US counties nationwide was performed, adjusting for county-level demographics, socioeconomic factors, comorbidities, and healthcare-associated behaviors. There was a moderate correlation between county PM2.5 and HF hospitalization among Medicare beneficiaries (r = 0.41) and a weak correlation between county PM2.5 and HF mortality (r = 0.08) (p-values

Suggested Citation

  • Edward W Chen & Khansa Ahmad & Sebhat Erqou & Wen-Chih Wu, 2022. "Particulate matter 2.5, metropolitan status, and heart failure outcomes in US counties: A nationwide ecologic analysis," PLOS ONE, Public Library of Science, vol. 17(12), pages 1-13, December.
    • Handle: RePEc:plo:pone00:0279777
    DOI: 10.1371/journal.pone.0279777
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