IDEAS home Printed from https://ideas.repec.org/a/plo/pone00/0278520.html
   My bibliography  Save this article

Inter-sleep stage variations in corrected QT interval differ between obstructive sleep apnea patients with and without stroke history

Author

Listed:
  • Serajeddin Ebrahimian
  • Saara Sillanmäki
  • Salla Hietakoste
  • Brett Duce
  • Antti Kulkas
  • Juha Töyräs
  • Timo Leppänen
  • Jukka A Lipponen
  • Samu Kainulainen

Abstract

Obstructive sleep apnea (OSA) is related to the progression of cardiovascular diseases (CVD); it is an independent risk factor for stroke and is also prevalent post-stroke. Furthermore, heart rate corrected QT (QTc) is an important predictor of the risk of arrhythmia and CVD. Thus, we aimed to investigate QTc interval variations in different sleep stages in OSA patients and whether nocturnal QTc intervals differ between OSA patients with and without stroke history. 18 OSA patients (apnea-hypopnea index (AHI)≥15) with previously diagnosed stroke and 18 OSA patients (AHI≥15) without stroke history were studied. Subjects underwent full polysomnography including an electrocardiogram measured by modified lead II configuration. RR, QT, and QTc intervals were calculated in all sleep stages. Regression analysis was utilized to investigate possible confounding effects of sleep stages and stroke history on QTc intervals. Compared to patients without previous stroke history, QTc intervals were significantly higher (β = 34, p

Suggested Citation

  • Serajeddin Ebrahimian & Saara Sillanmäki & Salla Hietakoste & Brett Duce & Antti Kulkas & Juha Töyräs & Timo Leppänen & Jukka A Lipponen & Samu Kainulainen, 2022. "Inter-sleep stage variations in corrected QT interval differ between obstructive sleep apnea patients with and without stroke history," PLOS ONE, Public Library of Science, vol. 17(12), pages 1-11, December.
    • Handle: RePEc:plo:pone00:0278520
    DOI: 10.1371/journal.pone.0278520
    as

    Download full text from publisher

    File URL: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0278520
    Download Restriction: no
    File URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0278520&type=printable
    Download Restriction: no
    File URL: https://libkey.io/10.1371/journal.pone.0278520?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:plo:pone00:0278520. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: plosone (email available below). General contact details of provider: https://journals.plos.org/plosone/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.