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Clinical and economic burden of surgical site infections in inpatient care in Germany: A retrospective, cross-sectional analysis from 79 hospitals

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  • Christian Eckmann
  • Axel Kramer
  • Ojan Assadian
  • Steffen Flessa
  • Claudia Huebner
  • Kristian Michnacs
  • Christian Muehlendyck
  • Kim Mirjam Podolski
  • Michael Wilke
  • Wolfgang Heinlein
  • David John Leaper

Abstract

Background: Surgical site infections (SSI) present a substantial burden to patients and healthcare systems. This study aimed to elucidate the prevalence of SSIs in German hospitals and to quantify their clinical and economic burden based on German hospital reimbursement data (G-DRG). Methods: This retrospective, cross-sectional study used a 2010–2016 G-DRG dataset to determine the prevalence of SSIs in hospital, using ICD-10-GM codes, after surgical procedures. The captured economic and clinical outcomes were used to quantify and compare resource use, reimbursement and clinical parameters for patients who had or did not have an SSI. Findings: Of the 4,830,083 patients from 79 hospitals, 221,113 were eligible. The overall SSI prevalence for the study period was 4.9%. After propensity-score matching, procedure type, immunosuppression and BMI ≥30 were found to significantly affect the risk of SSI (p

Suggested Citation

  • Christian Eckmann & Axel Kramer & Ojan Assadian & Steffen Flessa & Claudia Huebner & Kristian Michnacs & Christian Muehlendyck & Kim Mirjam Podolski & Michael Wilke & Wolfgang Heinlein & David John Le, 2022. "Clinical and economic burden of surgical site infections in inpatient care in Germany: A retrospective, cross-sectional analysis from 79 hospitals," PLOS ONE, Public Library of Science, vol. 17(12), pages 1-14, December.
    • Handle: RePEc:plo:pone00:0275970
    DOI: 10.1371/journal.pone.0275970
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