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Meta-analysis of the effectiveness and safety of Shenyankangfu tablets combined with losartan potassium in the treatment of chronic glomerulonephritis

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  • Pan-Feng Feng
  • Xiang-Fan Chen
  • Nan Sheng
  • Long-Xun Zhu

Abstract

Objective: To conduct a systematic review of the efficacy and safety of Shenyankangfu tablets in combination with losartan potassium in the treatment of chronic glomerulonephritis. Method: We searched PubMed, Embase, Cochrane Library, CNKI, WanFang Data, and WeiPu for comparative studies on Shenyankangfu tablets in combination with losartan potassium in the treatment of chronic glomerulonephritis. The search period runs from the establishment of the database until September 2021. Data extraction and quality evaluation were carried out on the documents that met the inclusion criteria, and a meta-analysis of the included literature was conducted using the RevMan5.3 software. Results: A total of 17 randomized controlled trials that met the inclusion criteria were included, with a total sample size of 1680 patients (841 patients in the study group and 839 in the control group). The effective rate was significantly higher in the study group than in the control group [RR = 1.22, 95% CI (1.16, 1.27), P

Suggested Citation

  • Pan-Feng Feng & Xiang-Fan Chen & Nan Sheng & Long-Xun Zhu, 2022. "Meta-analysis of the effectiveness and safety of Shenyankangfu tablets combined with losartan potassium in the treatment of chronic glomerulonephritis," PLOS ONE, Public Library of Science, vol. 17(10), pages 1-13, October.
    • Handle: RePEc:plo:pone00:0275735
    DOI: 10.1371/journal.pone.0275735
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