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Neutrophil count multiplied by D-dimer combined with pneumonia may better predict short-term outcomes in patients with acute ischemic stroke

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  • Yinting Xing
  • Wei Yang
  • Yingyu Jin
  • Yanhong Liu

Abstract

Objective: To investigate the predictive value of neutrophil, D-dimer and diseases associated with stroke for short-term outcomes of acute ischemic stroke (AIS). Methods: By collecting the subitems of laboratory data especially routine blood and coagulation test in AIS patients, and recording their clinical status, the correlation, regression and predictive value of each subitem with the short-term outcomes of AIS were analyzed. The predict model was constructed. Results: The neutrophil count multiplied by D-dimer (NDM) had the best predictive value among the subitems, and the area under the receiver operating characteristic (ROC) curve reached 0.804. When clinical information was not considered, the Youden index of NDM was calculated to be 0.48, corresponding to an NDM value of 7.78, a diagnostic sensitivity of 0.79, specificity of 0.69, negative predictive value of 96%. NDM were divided into 5 quintiles, the five grade of NDM (quintile) were

Suggested Citation

  • Yinting Xing & Wei Yang & Yingyu Jin & Yanhong Liu, 2022. "Neutrophil count multiplied by D-dimer combined with pneumonia may better predict short-term outcomes in patients with acute ischemic stroke," PLOS ONE, Public Library of Science, vol. 17(10), pages 1-14, October.
    • Handle: RePEc:plo:pone00:0275350
    DOI: 10.1371/journal.pone.0275350
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