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Long-term glucose-lowering effect of intermittently scanned continuous glucose monitoring for type 1 diabetes patients in poor glycaemic control from Region North Denmark: An observational real-world cohort study

Author

Listed:
  • Morten Hasselstrøm Jensen
  • Simon Lebech Cichosz
  • Peter Gustenhoff
  • Amar Nikontovic
  • Ole Hejlesen
  • Peter Vestergaard

Abstract

Background: Lowering glucose levels is a complex task for patients with type 1 diabetes, and they often lack contact with health care professionals. Intermittently scanned continuous glucose monitoring (isCGM) has the potential to aid them with blood glucose management at home. The aim of this study was to investigate the long-term effect of isCGM on HbA1c in type 1 diabetes patients with poor glycaemic control in a region-wide real-world setting. Methods: All patients with type 1 diabetes receiving an isCGM due to poor glycaemic control (≥70 mmol/mol [≥8.6%]) in the period of 2020–21 in Region North Denmark (“T1D-CGM”) were compared with all type 1 diabetes patients without isCGM (“T1D-NOCGM”) in the same period. A multiple linear regression model adjusted for age, sex, diabetes duration and use of continuous subcutaneous insulin infusion was constructed to estimate the difference in change from baseline HbA1c between the two groups and within subgroups of T1D-CGM. Results: A total of 2,527 patients (T1D-CGM: 897; T1D-NOCGM: 1,630) were included in the study. The estimated adjusted difference in change from baseline HbA1c between T1D-CGM vs T1D-NOCGM was -5.68 mmol/mol (95% CI: (-6.69 to -4.67 mmol/mol; p

Suggested Citation

  • Morten Hasselstrøm Jensen & Simon Lebech Cichosz & Peter Gustenhoff & Amar Nikontovic & Ole Hejlesen & Peter Vestergaard, 2022. "Long-term glucose-lowering effect of intermittently scanned continuous glucose monitoring for type 1 diabetes patients in poor glycaemic control from Region North Denmark: An observational real-world ," PLOS ONE, Public Library of Science, vol. 17(10), pages 1-10, October.
    • Handle: RePEc:plo:pone00:0274626
    DOI: 10.1371/journal.pone.0274626
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