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Post-systolic shortening index by echocardiography evaluation of dyssynchrony in the non-dilated and hypertrophied left ventricle

Author

Listed:
  • Yoshihito Saijo
  • Tom Kai Ming Wang
  • Nicholas Chan
  • Brett W Sperry
  • Dermot Phelan
  • Milind Y Desai
  • Brian Griffin
  • Richard A Grimm
  • Zoran B Popović

Abstract

Background: Post-systolic shortening index (PSI) is defined as myocardial shortening that occurs after aortic valve closure, and is an emerging measure of regional LV contractile dysfunction. PSI measurement variability amongst software vendor and its relationship with mechanical dyssynchrony and mechanical dispersion index (MDI) remains unknown. We evaluated PSI by speckle-tracking echocardiography from several vendors in patients with increased left ventricular wall thickness, and associations with MDI. Methods: This is a prospective cross-sectional study of 70 patients (36 hypertrophic cardiomyopathy [HCM], 18 cardiac amyloidosis and 16 healthy controls) undergoing clinically indicated echocardiography. PSI was measured using QLAB/aCMQ (Philips), QLAB/LV auto-trace (Philips), EchoPAC (GE), Velocity Vector Imaging (Siemens), and EchoInsight (EPSILON) software packages, and calculated as 100%×(post systolic strain–end-systole strain)/post systolic strain. Results: There was a significant difference in mean PSI among controls 2.1±0.6%, HCM 6.1±2.6% and cardiac amyloidosis 6.8±2.7% (p

Suggested Citation

  • Yoshihito Saijo & Tom Kai Ming Wang & Nicholas Chan & Brett W Sperry & Dermot Phelan & Milind Y Desai & Brian Griffin & Richard A Grimm & Zoran B Popović, 2022. "Post-systolic shortening index by echocardiography evaluation of dyssynchrony in the non-dilated and hypertrophied left ventricle," PLOS ONE, Public Library of Science, vol. 17(8), pages 1-12, August.
    • Handle: RePEc:plo:pone00:0273419
    DOI: 10.1371/journal.pone.0273419
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