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Risk factors of delirium in paediatric intensive care units: A meta-analysis

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  • Xuelian ZHU
  • Xiaoyan FENG
  • Jia LIN
  • Yanhong DING

Abstract

Background: Delirium is a brain dysfunction syndrome, which children have a higher incidence. At present, there have been more and more studies and reports on delirium in paediatric intensive care unit, but there are some differences in the risk factor results among different studies. To better manage delirium, this study was performed. Objective: To integrate and clarify the risk factors for delirium in paediatric intensive care unit. Methods: CNKI, CBMdisc, Wanfang Data Knowledge Service Platform, VIP, PubMed, Embase, Cochrane Library, JBI and PsycInfo were searched for relevant literature. The study subjects were patients in PICU and literature was included according to the PICOS principle. Literature screening and risk of bias assessment were mainly completed by two researchers, and RevMan 5.3 software and Stata software were used for data analysis. The GRADE systerm was used to assess the quality of evidence. Results: A total of 10 studies were included, all in English, involving 4343 children. Within the GRADE system, 4 indicators were scored A, 1 indicators were scored B, and 3 indicators were scored C regarding evidence levels. Three studies analysed the influence of developmental delay on the occurrence of delirium in PICU, total sample size of which was 1823, and the results showed that the combined effect was statistically significant [OR = 3.34, 95%CI(2.46–4.53), Z = 7.75, P

Suggested Citation

  • Xuelian ZHU & Xiaoyan FENG & Jia LIN & Yanhong DING, 2022. "Risk factors of delirium in paediatric intensive care units: A meta-analysis," PLOS ONE, Public Library of Science, vol. 17(7), pages 1-13, July.
    • Handle: RePEc:plo:pone00:0270639
    DOI: 10.1371/journal.pone.0270639
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