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A cross sectional study to examine factors influencing COVID-19 vaccine acceptance, hesitancy and refusal in urban and rural settings in Tamil Nadu, India

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  • Ashish Joshi
  • Krishna Mohan Surapaneni
  • Mahima Kaur
  • Ashruti Bhatt
  • Denis Nash
  • Ayman El-Mohandes

Abstract

The second wave of the COVID-19 pandemic left the Indian healthcare system overwhelmed. The severity of a third wave will depend on the success of the vaccination drive; however, even with a safe and effective COVID-19 vaccine, hesitancy can be an obstacle to achieving high levels of coverage. Our study aims to estimate the population’s acceptance of the COVID-19 vaccine in an Indian district. A pilot community-based cross-sectional study was conducted from March-May 2021. The data was collected from eight primary health centres in Tamil Nadu. The eligible study participants were interviewed using a self-constructed questionnaire. A total of 3,130 individuals responded to the survey. Multinomial logistic regression was performed to assess the factors influencing COVID-19 vaccine hesitancy and refusal. Results of our study showed that 46% percent (n = 1432) of the respondents would accept the COVID-19 vaccine if available. Acceptance for the COVID-19 vaccine was higher among males (54%), individuals aged 18-24years (62%), those with higher education (77%), having the higher income (73%), and employed (51%). Individuals with no education (OR: 2.799, 95% CI = 1.103–7.108), and low income (OR: OR: 10.299, 95% CI: 4.879–21.741), were significant predictors of vaccine hesitancy (p

Suggested Citation

  • Ashish Joshi & Krishna Mohan Surapaneni & Mahima Kaur & Ashruti Bhatt & Denis Nash & Ayman El-Mohandes, 2022. "A cross sectional study to examine factors influencing COVID-19 vaccine acceptance, hesitancy and refusal in urban and rural settings in Tamil Nadu, India," PLOS ONE, Public Library of Science, vol. 17(6), pages 1-17, June.
  • Handle: RePEc:plo:pone00:0269299
    DOI: 10.1371/journal.pone.0269299
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