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A database study of clinical and economic burden of invasive meningococcal disease in France

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  • Liping Huang
  • Stéphane Fievez
  • Mélanie Goguillot
  • Lucile Marié
  • Stève Bénard
  • Anne Elkaïm
  • Myint Tin Tin Htar

Abstract

Objective: Invasive meningococcal disease (IMD) is life-threatening and associated with substantial morbidity and mortality. The study aimed to examine the clinical characteristics and hospital-based healthcare resource use and related costs following IMD diagnosis in France. Methods: Patients admitted to hospitals due to IMD between 2014 and 2016 were selected from the French hospital discharge database (PMSI). Demographics, clinical outcomes and health utilization (HRU) during index hospitalization were described. HRU and costs during the follow-up period were also examined. A generalized linear model was applied to examine 1-year costs after index hospitalization adjusting for age, type of IMD and presence of sequelae at index hospitalization. Results: A total of 1,344 patients were identified. About 30% cases were in children

Suggested Citation

  • Liping Huang & Stéphane Fievez & Mélanie Goguillot & Lucile Marié & Stève Bénard & Anne Elkaïm & Myint Tin Tin Htar, 2022. "A database study of clinical and economic burden of invasive meningococcal disease in France," PLOS ONE, Public Library of Science, vol. 17(4), pages 1-12, April.
    • Handle: RePEc:plo:pone00:0267786
    DOI: 10.1371/journal.pone.0267786
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    References listed on IDEAS

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    1. Bing Wang & Renee Santoreneos & Hossein Afzali & Lynne Giles & Helen Marshall, 2018. "Costs of Invasive Meningococcal Disease: A Global Systematic Review," PharmacoEconomics, Springer, vol. 36(10), pages 1201-1222, October.
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