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Role of the choroidal vascularity index in branch retinal vein occlusion (BRVO) with macular edema

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  • Bo-Een Hwang
  • Mirinae Kim
  • Young-Hoon Park

Abstract

Purpose: To assess choroidal vasculature changes in eyes with branch retinal vein occlusion (BRVO) and macular edema (ME) using the choroidal vascularity index (CVI) and evaluate the effectiveness of CVI as a prognostic biomarker. Methods: 35 patients with monocular BRVO and ME were analyzed retrospectively. Luminal and stromal areas in choroids of swept-source optical coherence tomography were calculated using the image binarization technique. The CVI was calculated as the ratio of the luminal to total choroidal area. The CVI of BRVO and ME eyes were compared with that of the unaffected fellow and post anti-vascular endothelial growth factor (VEGF) injected eyes. A regression analysis was performed on the choroidal parameters, logMAR visual acuity (VA) two years post disease onset and central macula thickness (CMT). Results: The CVI of BRVO and ME eyes was significantly lower than the fellow and post-injected eyes (p

Suggested Citation

  • Bo-Een Hwang & Mirinae Kim & Young-Hoon Park, 2021. "Role of the choroidal vascularity index in branch retinal vein occlusion (BRVO) with macular edema," PLOS ONE, Public Library of Science, vol. 16(10), pages 1-11, October.
  • Handle: RePEc:plo:pone00:0258728
    DOI: 10.1371/journal.pone.0258728
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