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Risk factors for unfavorable clinical outcomes in patients with brain abscess in South Korea

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  • Yun Suk Cho
  • Yu Jin Sohn
  • Jong Hoon Hyun
  • Yae Jee Baek
  • Moo Hyun Kim
  • Jung Ho Kim
  • Jin Young Ahn
  • Su Jin Jeong
  • Nam Su Ku
  • Jun Yong Choi
  • Joon-Sup Yeom
  • Young Goo Song

Abstract

Background: Brain abscess can be life-threatening and manifest various neurological findings, although the mortality rate has decreased recently. We investigated the risk factors for unfavorable outcomes of patients with brain abscess. Methods: A retrospective cohort study examined patients with brain abscess seen from May 2005 to December 2018 in a tertiary care hospital in Seoul, South Korea. We reviewed the medical records for clinical findings, therapeutic modalities, and prognostic factors of brain abscess. Unfavorable clinical outcomes were defined as death, moderate to severe disability with neurological deficits, or vegetative state at 1 year or at the time of discharge from outpatient follow-up. Results: The study enrolled 135 patients: 65.2% were males; the mean age was 56 years. 35.6% had unfavorable outcomes. In multivariate analysis, higher Sequential Organ Failure Assessment (SOFA) (p

Suggested Citation

  • Yun Suk Cho & Yu Jin Sohn & Jong Hoon Hyun & Yae Jee Baek & Moo Hyun Kim & Jung Ho Kim & Jin Young Ahn & Su Jin Jeong & Nam Su Ku & Jun Yong Choi & Joon-Sup Yeom & Young Goo Song, 2021. "Risk factors for unfavorable clinical outcomes in patients with brain abscess in South Korea," PLOS ONE, Public Library of Science, vol. 16(9), pages 1-9, September.
    • Handle: RePEc:plo:pone00:0257541
    DOI: 10.1371/journal.pone.0257541
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