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Acute kidney injury and acute kidney recovery following Transcatheter Aortic Valve Replacement

Author

Listed:
  • Marilou Peillex
  • Benjamin Marchandot
  • Kensuke Matsushita
  • Eric Prinz
  • Sebastien Hess
  • Antje Reydel
  • Marion Kibler
  • Adrien Carmona
  • Antonin Trimaille
  • Joe Heger
  • Hélène Petit-Eisenmann
  • Annie Trinh
  • Laurence Jesel
  • Patrick Ohlmann
  • Olivier Morel

Abstract

Background: Acute kidney injury (AKI) is associated with a dismal prognosis in Transcatheter Aortic Valve replacement (TAVR). Acute kidney recovery (AKR), a phenomenon reverse to AKI has recently been associated with better outcomes. Methods: Between November 2012 to May 2018, we explored consecutive patients referred to our Heart Valve Center for TAVR. AKI was defined according to the VARC-2 definition. Mirroring the VARC-2 definition of AKI, AKR was defined as a decrease in serum creatinine (≥50%) or ≥25% improvement in GFR up to 72 hours after TAVR. Results: AKI and AKR were respectively observed in 8.3 and 15.7% of the 574 patients included. AKI and AKR patients were associated to more advanced kidney disease at baseline. At a median follow-up of 608 days (range 355–893), AKI and AKR patients experienced an increased cardiovascular mortality compared to unchanged renal function patients (14.6% and 17.8% respectively, vs. 8.1%, CI 95%, p

Suggested Citation

  • Marilou Peillex & Benjamin Marchandot & Kensuke Matsushita & Eric Prinz & Sebastien Hess & Antje Reydel & Marion Kibler & Adrien Carmona & Antonin Trimaille & Joe Heger & Hélène Petit-Eisenmann & Anni, 2021. "Acute kidney injury and acute kidney recovery following Transcatheter Aortic Valve Replacement," PLOS ONE, Public Library of Science, vol. 16(8), pages 1-14, August.
    • Handle: RePEc:plo:pone00:0255806
    DOI: 10.1371/journal.pone.0255806
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