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Availability of preoperative neutrophil-lymphocyte ratio to predict postoperative delirium after head and neck free-flap reconstruction: A retrospective study

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  • Hirotaka Kinoshita
  • Junichi Saito
  • Daiki Takekawa
  • Tasuku Ohyama
  • Tetsuya Kushikata
  • Kazuyoshi Hirota

Abstract

Postoperative delirium (POD) is a well-recognized postoperative complication and is associated with increased morbidity and mortality. We investigated whether the preoperative neutrophil-lymphocyte ratio (NLR) could be an effective predictor of POD after head and neck free-flap reconstruction. This was a single-center, retrospective, observational study. We analyzed the perioperative data of patients who had undergone elective head and neck free-flap reconstruction surgery. POD was assessed with the Intensive Care Delirium Screening Checklist (ICDSC) during admission to our intensive care unit (ICU). POD was defined as an ICDSC score ≥4. Risk factors for POD were evaluated by univariate and multivariate logistic regression analysis. We included 97 patients. The incidence of POD was 20.6% (20/97). Significantly longer ICU stays were observed in the patients with POD compared to those without POD (median [interquartile range]: 5 [4–6] vs. 4 [4–5], p = 0.031). Higher preoperative NLR values (3 3.0 (adjusted Odds Ratio: 23.6, 95% Confidence Interval: 6.6–85.1; p

Suggested Citation

  • Hirotaka Kinoshita & Junichi Saito & Daiki Takekawa & Tasuku Ohyama & Tetsuya Kushikata & Kazuyoshi Hirota, 2021. "Availability of preoperative neutrophil-lymphocyte ratio to predict postoperative delirium after head and neck free-flap reconstruction: A retrospective study," PLOS ONE, Public Library of Science, vol. 16(7), pages 1-13, July.
    • Handle: RePEc:plo:pone00:0254654
    DOI: 10.1371/journal.pone.0254654
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