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Prevalence and incidence of diabetic peripheral neuropathy in Latin America and the Caribbean: A systematic review and meta-analysis

Author

Listed:
  • Marlon Yovera-Aldana
  • Victor Velásquez-Rimachi
  • Andrely Huerta-Rosario
  • M D More-Yupanqui
  • Mariela Osores-Flores
  • Ricardo Espinoza
  • Fradis Gil-Olivares
  • César Quispe-Nolazco
  • Flor Quea-Vélez
  • Christian Morán-Mariños
  • Isabel Pinedo-Torres
  • Carlos Alva-Diaz
  • Kevin Pacheco-Barrios

Abstract

Aims: The objective of this systematic review and meta-analysis is to estimate the prevalence and incidence of diabetic peripheral neuropathy (DPN) in Latin America and the Caribbean (LAC). Materials and methods: We searched MEDLINE, SCOPUS, Web of Science, EMBASE and LILACS databases of published observational studies in LAC up to December 2020. Meta-analyses of proportions were performed using random-effects models using Stata Program 15.1. Heterogeneity was evaluated through sensitivity, subgroup, and meta-regression analyses. Evidence certainty was performed with the GRADE approach. Results: Twenty-nine studies from eight countries were included. The estimated prevalence of DPN was 46.5% (95%CI: 38.0–55.0) with a significant heterogeneity (I2 = 98.2%; p

Suggested Citation

  • Marlon Yovera-Aldana & Victor Velásquez-Rimachi & Andrely Huerta-Rosario & M D More-Yupanqui & Mariela Osores-Flores & Ricardo Espinoza & Fradis Gil-Olivares & César Quispe-Nolazco & Flor Quea-Vélez &, 2021. "Prevalence and incidence of diabetic peripheral neuropathy in Latin America and the Caribbean: A systematic review and meta-analysis," PLOS ONE, Public Library of Science, vol. 16(5), pages 1-29, May.
    • Handle: RePEc:plo:pone00:0251642
    DOI: 10.1371/journal.pone.0251642
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