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Improved privacy preserving method for periodical SRS publishing

Author

Listed:
  • Wei Huang
  • Tong Yi
  • Haibin Zhu
  • Wenqian Shang
  • Weiguo Lin

Abstract

Spontaneous reporting systems (SRSs) are used to collect adverse drug events (ADEs) for their evaluation and analysis. Periodical SRS data publication gives rise to a problem where sensitive, private data can be discovered through various attacks. The existing SRS data publishing methods are vulnerable to Medicine Discontinuation Attack(MD-attack) and Substantial symptoms-attack(SS-attack). To remedy this problem, an improved periodical SRS data publishing—PPMS(k, θ, ɑ)-bounding is proposed. This new method can recognize MD-attack by ensuring that each equivalence group contains at least k new medicine discontinuation records. The SS-attack can be thwarted using a heuristic algorithm. Theoretical analysis indicates that PPMS(k, θ, ɑ)-bounding can thwart the above-mentioned attacks. The experimental results also demonstrate that PPMS(k, θ, ɑ)-bounding can provide much better protection for privacy than the existing method and the new method dose not increase the information loss. PPMS(k, θ, ɑ)-bounding can improve the privacy, guaranteeing the information usability of the released tables.

Suggested Citation

  • Wei Huang & Tong Yi & Haibin Zhu & Wenqian Shang & Weiguo Lin, 2021. "Improved privacy preserving method for periodical SRS publishing," PLOS ONE, Public Library of Science, vol. 16(4), pages 1-21, April.
  • Handle: RePEc:plo:pone00:0250457
    DOI: 10.1371/journal.pone.0250457
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