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Long-term maxillary anteroposterior changes following maxillary protraction with or without expansion: A meta-analysis and meta-regression

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  • Wei-Cheng Lee
  • Yi-Shing Shieh
  • Yu-Fang Liao
  • Cho-Hao Lee
  • Chiung Shing Huang

Abstract

Background: Maxillary protraction with or without expansion is a widely known orthopedic treatment modality in growing skeletal Class III patients. However, limited data are available regarding the outcomes of long-term changes in the maxilla. Aim of this meta-analysis was to assess the effectiveness of the long-term maxillary anteroposterior changes following a facemask therapy with or without rapid maxillary expansion in growing skeletal Class III patients. Methods: A comprehensive literature search was conducted using the databases of PubMed, Science Direct, Web of Science, and Embase. Randomized controlled trials and cohort studies, published up to Sep. 2020, with maxillary protraction and/or expansion as keywords were included in this meta-analysis. Risk of bias within and across studies were assessed using the Cochrane tools (RoB2.0 and ROBINS-I) and GRADE approach. Overall and subgroup comparisons with the random-effect model were performed in this meta-analysis. Meta-regression models were designed to determine potential heterogeneity. Results: There was a statistically significant increase (Mean difference, 2.29°; 95% confidence interval, 1.86–2.73; and p

Suggested Citation

  • Wei-Cheng Lee & Yi-Shing Shieh & Yu-Fang Liao & Cho-Hao Lee & Chiung Shing Huang, 2021. "Long-term maxillary anteroposterior changes following maxillary protraction with or without expansion: A meta-analysis and meta-regression," PLOS ONE, Public Library of Science, vol. 16(2), pages 1-18, February.
    • Handle: RePEc:plo:pone00:0247027
    DOI: 10.1371/journal.pone.0247027
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