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Complete symptom resolution as predictor of Helicobacter pylori eradication and factors affecting symptom resolution: Prospective follow up study

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  • Endalew Gebeyehu
  • Desalegn Nigatu
  • Ephrem Engidawork

Abstract

Background: Symptom resolution is the most common clinical practice during assessment and evaluation of helicobacter pylori infected patients after employing eradication therapy. Objective: Prediction of eradication of H. pylori with symptom resolution and assess factors affecting symptom resolution. Method: Facility based follow up study was done on consented H. pylori positive adult patients who received standard triple therapy consisting of a proton pump inhibitor, amoxicillin, and clarithromycin from May 2016 to April 2018 at Bahir Dar city in Ethiopia. Sociodemographic and clinical data was collected before and after eradication therapy by using pre-developed structured questionnaire. Both positive and negative predictive values were calculated. SPSS version 23 was used to conduct bivariate and backward stepwise multivariate logistic regression to analyze data. P-value

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  • Endalew Gebeyehu & Desalegn Nigatu & Ephrem Engidawork, 2021. "Complete symptom resolution as predictor of Helicobacter pylori eradication and factors affecting symptom resolution: Prospective follow up study," PLOS ONE, Public Library of Science, vol. 16(2), pages 1-15, February.
    • Handle: RePEc:plo:pone00:0246624
    DOI: 10.1371/journal.pone.0246624
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