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Delirium as a predictor of mortality and disability among hospitalized patients in Zambia

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  • Justin K Banerdt
  • Kondwelani Mateyo
  • Li Wang
  • Christopher J Lindsell
  • Elisabeth D Riviello
  • Deanna Saylor
  • Douglas C Heimburger
  • E Wesley Ely

Abstract

Objective: To study the epidemiology and outcomes of delirium among hospitalized patients in Zambia. Methods: We conducted a prospective cohort study at the University Teaching Hospital in Lusaka, Zambia, from October 2017 to April 2018. The primary exposure was delirium duration over the initial 3 days of hospitalization, assessed daily using the Brief Confusion Assessment Method. The primary outcome was 6-month mortality. Secondary outcomes included 6-month disability, evaluated using the World Health Organization Disability Assessment Schedule 2.0. Findings: 711 adults were included (median age, 39 years; 461 men; 459 medical, 252 surgical; 323 with HIV). Delirium prevalence was 48.5% (95% CI, 44.8%-52.3%). 6-month mortality was higher for delirious participants (44.6% [39.3%-50.1%]) versus non-delirious participants (20.0% [15.4%-25.2%]; P

Suggested Citation

  • Justin K Banerdt & Kondwelani Mateyo & Li Wang & Christopher J Lindsell & Elisabeth D Riviello & Deanna Saylor & Douglas C Heimburger & E Wesley Ely, 2021. "Delirium as a predictor of mortality and disability among hospitalized patients in Zambia," PLOS ONE, Public Library of Science, vol. 16(2), pages 1-15, February.
    • Handle: RePEc:plo:pone00:0246330
    DOI: 10.1371/journal.pone.0246330
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