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Sepsis recording in primary care electronic health records, linked hospital episodes and mortality records: Population-based cohort study in England

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  • Emma Rezel-Potts
  • Martin C Gulliford
  • the Safe AB Study Group

Abstract

Background: Sepsis is a growing concern for health systems, but the epidemiology of sepsis is poorly characterised. We evaluated sepsis recording across primary care electronic records, hospital episodes and mortality registrations. Methods and findings: Cohort study including 378 general practices in England from Clinical Practice Research Datalink (CPRD) GOLD database from 2002–2017 with 36,209,676 patient-years of follow-up with linked Hospital Episode Statistics (HES) and Office for National Statistics (ONS) mortality registrations. Incident sepsis episodes were identified for each source. Concurrent records from different sources were identified and age-standardised and age-specific incidence rates compared. Logistic regression analysis evaluated associations of gender, age-group, fifth of deprivation and period of diagnosis with concurrent sepsis recording. Conclusion: Explicit recording of ‘sepsis’ is inconsistent across healthcare sectors with a high proportion of non-concurrent records. Incidence estimates are higher when linked data are analysed.

Suggested Citation

  • Emma Rezel-Potts & Martin C Gulliford & the Safe AB Study Group, 2020. "Sepsis recording in primary care electronic health records, linked hospital episodes and mortality records: Population-based cohort study in England," PLOS ONE, Public Library of Science, vol. 15(12), pages 1-12, December.
    • Handle: RePEc:plo:pone00:0244764
    DOI: 10.1371/journal.pone.0244764
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