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Usefulness of serial post-systolic shortening by speckle tracking echocardiography to predict major adverse cardiovascular events and segmental function improvement after acute myocardial infarction

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  • Ju-Feng Hsiao
  • Kuo-Li Pan
  • Chi-Ming Chu
  • Shih-Tai Chang
  • Chang-Min Chung
  • Jen-Te Hsu

Abstract

Purpose: The aim is to determine whether serial post-systolic shortening (PSS) using speckle tracking echocardiography (STE) could predict major adverse cardiovascular events (MACE), especially symptom-driven infarct-related artery (IRA) revascularization and improvement in segmental function in post-myocardial infarction patients. Methods/Results: Ninety-four patients (average age 61.1 ± 12.5 y, 84 [84.9%] male) with new-onset acute myocardial infarction were enrolled. Serial echocardiography was performed during the initial presentation, and at 3, 6 and 12 months after admission. PSS, strain and systolic strain rate were calculated using STE. Improvement in segmental function was defined as a decrease of ≧1 grade in wall motion score. During the follow-up (29.4 ± 12.7months), 22 patients (23.4%) had MACE and 17 patients had symptom-driven IRA revascularization. In multivariate model, PSS at 3 months was independently predictive for symptom-driven IRA revascularization (Hazard ratio (HR) = 0.5, 95% CI = 0.26–0.97) and for MACE (HR = 0.4, 95% CI = 0.24–0.67) (p

Suggested Citation

  • Ju-Feng Hsiao & Kuo-Li Pan & Chi-Ming Chu & Shih-Tai Chang & Chang-Min Chung & Jen-Te Hsu, 2020. "Usefulness of serial post-systolic shortening by speckle tracking echocardiography to predict major adverse cardiovascular events and segmental function improvement after acute myocardial infarction," PLOS ONE, Public Library of Science, vol. 15(12), pages 1-16, December.
    • Handle: RePEc:plo:pone00:0244589
    DOI: 10.1371/journal.pone.0244589
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