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COVID-19 gender susceptibility and outcomes: A systematic review

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  • Ines Lakbar
  • David Luque-Paz
  • Jean-Louis Mege
  • Sharon Einav
  • Marc Leone

Abstract

Background: Epidemiological differences between men and women have been reported with regards to sepsis, influenza and severe coronavirus infections including SARS-CoV and MERS-CoV. Aim: To systematically review the literature relating to men versus women on SARS-CoV-2 in order to seek differences in disease characteristics (e.g. infectivity, severity) and outcomes (e.g. mortality). Methods: We searched 3 electronic databases up or observational studies reporting differences between men and women in the SARS-CoV-2 disease characteristics stated. We identified and included 47 studies, reporting data for 21,454 patients mainly from China. Results: The unadjusted mortality rates of men were higher than those of women, with a mortality OR 0.51 [0.42, 0.61] (p

Suggested Citation

  • Ines Lakbar & David Luque-Paz & Jean-Louis Mege & Sharon Einav & Marc Leone, 2020. "COVID-19 gender susceptibility and outcomes: A systematic review," PLOS ONE, Public Library of Science, vol. 15(11), pages 1-15, November.
    • Handle: RePEc:plo:pone00:0241827
    DOI: 10.1371/journal.pone.0241827
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