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Physiological changes in retinal layers thicknesses measured with swept source optical coherence tomography

Author

Listed:
  • Elisa Viladés
  • Amaya Pérez-del Palomar
  • José Cegoñino
  • Javier Obis
  • María Satue
  • Elvira Orduna
  • Luis E Pablo
  • Marta Ciprés
  • Elena Garcia-Martin

Abstract

Purpose: To evaluate the physiological changes related with age of all retinal layers thickness measurements in macular and peripapillary areas in healthy eyes. Methods: Wide protocol scan (with a field of view of 12x9 cm) from Triton SS-OCT instrument (Topcon Corporation, Japan) was performed 463 heathy eyes from 463 healthy controls. This protocol allows to measure the thickness of the following layers: Retina, Retinal nerve fiber layer (RNFL), Ganglion cell layer (GCL +), GCL++ and choroid. In those layers, mean thickness was compared in four groups of ages: Group 1 (71 healthy subjects aged between 20 and 34 years); Group 2 (65 individuals aged 35–49 years), Group 3 (230 healthy controls aged 50–64 years) and Group 4 (97 healthy subjects aged 65–79 years). Results: The most significant thinning of all retinal layers occurs particularly in the transition from group 2 to group 3, especially in temporal superior quadrant at RNFL, GCL++ and retinal layers (p≤0.001), and temporal superior, temporal inferior, and temporal half in choroid layer (p

Suggested Citation

  • Elisa Viladés & Amaya Pérez-del Palomar & José Cegoñino & Javier Obis & María Satue & Elvira Orduna & Luis E Pablo & Marta Ciprés & Elena Garcia-Martin, 2020. "Physiological changes in retinal layers thicknesses measured with swept source optical coherence tomography," PLOS ONE, Public Library of Science, vol. 15(10), pages 1-14, October.
    • Handle: RePEc:plo:pone00:0240441
    DOI: 10.1371/journal.pone.0240441
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