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Characteristics of academic publications, preprints, and registered clinical trials on the COVID-19 pandemic

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  • Silvia Gianola
  • Tiago S Jesus
  • Silvia Bargeri
  • Greta Castellini

Abstract

The COVID-19 pandemic has unleashed a deluge of publications. For this cross-sectional study we compared the amount and reporting characteristics of COVID-19-related academic articles and preprints and the number of ongoing clinical trials and systematic reviews. To do this, we searched the PubMed database of citations and abstracts for published life science journals by using appropriate combinations of medical subject headings (MeSH terms), and the COVID-19 section of the MedRxiv and BioRxiv archives up to 20 May 2020 (21 weeks). In addition, we searched Clinicaltrial.gov, Chinese Clinical Trial Registry, EU Clinical Trials Register, and 15 other trial registers, as well as PROSPERO, the international prospective register of systematic reviews. The characteristics of each publication were extracted. Regression analyses and Z tests were used to detect publication trends and their relative proportions. A total of 3635 academic publications and 3805 preprints were retrieved. Only 8.6% (n = 329) of the preprints were already published in indexed journals. The number of academic and preprint publications increased significantly over time (p

Suggested Citation

  • Silvia Gianola & Tiago S Jesus & Silvia Bargeri & Greta Castellini, 2020. "Characteristics of academic publications, preprints, and registered clinical trials on the COVID-19 pandemic," PLOS ONE, Public Library of Science, vol. 15(10), pages 1-15, October.
    • Handle: RePEc:plo:pone00:0240123
    DOI: 10.1371/journal.pone.0240123
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