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Risk of metabolic syndrome in patients with lichen planus: A systematic review and meta-analysis

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  • Jieya Ying
  • Wenzhong Xiang
  • Yu Qiu
  • Xiaofang Zeng

Abstract

Background: Studies have investigated whether patients with lichen planus are at a high risk of metabolic syndrome; however, currently, no conclusive data are available in this regard. Objective: This meta-analysis was performed to analyze the published literature investigating the association between metabolic syndrome and lichen planus. Method: Two reviewers independently searched 4 databases (PubMed, Embase, the Cochrane Library and Web of Science) for observational studies assessing the prevalence of metabolic syndrome in patients with lichen planus. Review Manager 5.3 software was used to statistically analyze the data. Results: 200 relevant articles were searched. After a further reading, 12 studies with 1422 participants (715 with LP and 707 controls) fulfilled the eligibility criteria. Overall, the pooled odds ratio based on random effects analysis was 2.81 (95% confidence interval: 1.79–4.41, P

Suggested Citation

  • Jieya Ying & Wenzhong Xiang & Yu Qiu & Xiaofang Zeng, 2020. "Risk of metabolic syndrome in patients with lichen planus: A systematic review and meta-analysis," PLOS ONE, Public Library of Science, vol. 15(8), pages 1-13, August.
    • Handle: RePEc:plo:pone00:0238005
    DOI: 10.1371/journal.pone.0238005
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