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Predictive factors of first dosage intravenous immunoglobulin-related adverse effects in children

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Listed:
  • Jun Kubota
  • Shin-ichiro Hamano
  • Atsuro Daida
  • Erika Hiwatari
  • Satoru Ikemoto
  • Yuko Hirata
  • Ryuki Matsuura
  • Daishi Hirano

Abstract

Background: Intravenous immunoglobulin (IVIG) therapy is used in the treatment of various diseases, and IVIG-related adverse effects (IVIG-AEs) vary from mild to severe. However, the mechanisms underlying IVIG-AEs and the potential predictive factors are not clear. This study investigated whether certain IVIG-AEs can be predicted before IVIG administration. Study design and methods: This retrospective cohort study at the Division of Neurology, Saitama Children’s Medical Center included patients enrolled from 2008 to 2018 who were

Suggested Citation

  • Jun Kubota & Shin-ichiro Hamano & Atsuro Daida & Erika Hiwatari & Satoru Ikemoto & Yuko Hirata & Ryuki Matsuura & Daishi Hirano, 2020. "Predictive factors of first dosage intravenous immunoglobulin-related adverse effects in children," PLOS ONE, Public Library of Science, vol. 15(1), pages 1-12, January.
  • Handle: RePEc:plo:pone00:0227796
    DOI: 10.1371/journal.pone.0227796
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