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Nonarteritic anterior ischemic optic neuropathy is associated with cerebral small vessel disease

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  • Min Seok Kim
  • Han Yeong Jeong
  • Kwan Hyuk Cho
  • Seung Won Oh
  • Seong Jun Byun
  • Se Joon Woo
  • Hee Kyung Yang
  • Jeong Min Hwang
  • Kyu Hyung Park
  • Chi Kyung Kim
  • Sang Jun Park

Abstract

We investigated the presence of cerebral small vessel disease (SVD) in patients with nonarteritic anterior ischemic optic neuropathy (NAION) compared to control subjects without NAION to identify the association between NAION and cerebral SVD. We retrospectively reviewed the cases of 63 patients with NAION and 2749 control subjects without any neurologic and ocular diseases including NAION who underwent careful medical interviews, ophthalmic examinations, and magnetic resonance imaging (MRI) studies of the brain. We assessed and compared the degree of cerebral SVD on the MRIs. The patients with NAION presented with cerebral SVD more frequently than controls (68% versus 37%, respectively, p

Suggested Citation

  • Min Seok Kim & Han Yeong Jeong & Kwan Hyuk Cho & Seung Won Oh & Seong Jun Byun & Se Joon Woo & Hee Kyung Yang & Jeong Min Hwang & Kyu Hyung Park & Chi Kyung Kim & Sang Jun Park, 2019. "Nonarteritic anterior ischemic optic neuropathy is associated with cerebral small vessel disease," PLOS ONE, Public Library of Science, vol. 14(11), pages 1-10, November.
  • Handle: RePEc:plo:pone00:0225322
    DOI: 10.1371/journal.pone.0225322
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