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Candida blood stream infections observed between 2011 and 2016 in a large Italian University Hospital: A time-based retrospective analysis on epidemiology, biofilm production, antifungal agents consumption and drug-susceptibility

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Listed:
  • Grazia Brunetti
  • Anna Sara Navazio
  • Alessandro Giuliani
  • Alessandra Giordano
  • Enrica Maria Proli
  • Guido Antonelli
  • Giammarco Raponi

Abstract

Candida bloodstream infection (BSI) represents a growing infective problem frequently associated to biofilm production due to the utilization of intravascular devices. Candida species distribution (n = 612 strains), their biofilm production and hospital antifungal drug consumption were evaluated in different wards of a tertiary care academic hospital in Italy during the years 2011–2016. In the considered time window, an increasing number of Candida BSI (p = 0.005) and of biofilm producing strains were observed (p

Suggested Citation

  • Grazia Brunetti & Anna Sara Navazio & Alessandro Giuliani & Alessandra Giordano & Enrica Maria Proli & Guido Antonelli & Giammarco Raponi, 2019. "Candida blood stream infections observed between 2011 and 2016 in a large Italian University Hospital: A time-based retrospective analysis on epidemiology, biofilm production, antifungal agents consum," PLOS ONE, Public Library of Science, vol. 14(11), pages 1-17, November.
    • Handle: RePEc:plo:pone00:0224678
    DOI: 10.1371/journal.pone.0224678
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