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A comparison between measured and calculated central venous oxygen saturation in critically ill patients

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  • Bruno De Oliveira
  • Malligere Prasanna
  • Malcolm Lemyze
  • Laurent Tronchon
  • Didier Thevenin
  • Jihad Mallat

Abstract

Background: Central venous oxygen saturation (ScvO2) is often used to help to guide resuscitation of critically ill patients. The standard gold technique for ScvO2 measurement is the co-oximetry (Co-oximetry_ScvO2), which is usually incorporated in most recent blood gas analyzers. However, in some hospitals, those machines are not available and only calculated ScvO2 (Calc_ScvO2) is provided. Therefore, we aimed to investigate the agreement between Co-oximetry_ScvO2 and Calc_ScvO2 in a general population of critically ill patients and septic shock patients. Methods: A total of 100 patients with a central venous catheter were included in the study. One hundred central venous blood samples were collected and analyzed using the same point-of-care blood gas analyzer, which provides both the calculated and measured ScvO2 values. Bland and Altman plot, intra-class correlation coefficient (ICC), and Cohen’s Kappa coefficient were used to assess the agreement between Co-oximetry_ScvO2 and Calc_ScvO2. Multiple linear regression analysis was performed to investigate the independent explanatory variables of the difference between Co-oximetry_ScvO2 and Calc_ScvO2. Results: In all population, Bland and Altman’s analysis showed poor agreement (+4.5 [-7.1, +16.1]%) between the two techniques. The ICC was 0.754 [(95% CI: 0.393–0.880), P

Suggested Citation

  • Bruno De Oliveira & Malligere Prasanna & Malcolm Lemyze & Laurent Tronchon & Didier Thevenin & Jihad Mallat, 2018. "A comparison between measured and calculated central venous oxygen saturation in critically ill patients," PLOS ONE, Public Library of Science, vol. 13(11), pages 1-13, November.
    • Handle: RePEc:plo:pone00:0206868
    DOI: 10.1371/journal.pone.0206868
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