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Validation of the blood gas analyzer for pH measurements in IVF culture medium: Prevent suboptimal culture conditions

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  • Juan D N Diaz de Pool
  • Sjoerd A A Van Den Berg
  • Gonneke S K Pilgram
  • Bartholomeus E P B Ballieux
  • Lucia A J Van Der Westerlaken

Abstract

Measurement of pH in IVF-media using the blood gas analyzer (BGA) requires validation, because IVF-media is outside the intended scope of the BGA. To determine whether the Siemens Rapidpoint 500 BGA is suitable for pH measurements in IVF-media this study will validate the BGA and assess its accuracy. In this method comparison study, the pH of over three hundred IVF-media samples was measured with the BGA and a pH electrode (Hanna pH checker). The precision of both the BGA and the pH electrode were excellent (coefficient variation

Suggested Citation

  • Juan D N Diaz de Pool & Sjoerd A A Van Den Berg & Gonneke S K Pilgram & Bartholomeus E P B Ballieux & Lucia A J Van Der Westerlaken, 2018. "Validation of the blood gas analyzer for pH measurements in IVF culture medium: Prevent suboptimal culture conditions," PLOS ONE, Public Library of Science, vol. 13(11), pages 1-10, November.
    • Handle: RePEc:plo:pone00:0206707
    DOI: 10.1371/journal.pone.0206707
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