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Optical coherence tomography findings as a predictor of clinical course in patients with branch retinal vein occlusion treated with ranibizumab

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  • Akira Shiono
  • Jiro Kogo
  • Hiroki Sasaki
  • Ryo Yomoda
  • Tatsuya Jujo
  • Naoto Tokuda
  • Yasushi Kitaoka
  • Hitoshi Takagi

Abstract

Purpose: To examine the relationship between optical coherence tomography (OCT) images and clinical course in eyes with branch retinal vein occlusion (BRVO) treated with intravitreal ranibizumab injection (IVR). Design: Prospective cohort study. Participants: Thirty eyes of 30 patients with BRVO treated with IVR. Methods: All patients received 1 initial IVR followed by repeated injections in the pro re nata (PRN) regimen. Correlations between logarithm of minimum angle of resolution best-corrected visual acuity (logMAR BCVA) or number of IVRs after 12 months and OCT parameters including the external limiting membrane (ELM), ellipsoid zone (EZ), interdigitation zone (IZ), and photoreceptor outer segment (PROS) length at first resolution of macular edema (ME) were assessed. Resolution of ME was defined as central foveal thickness

Suggested Citation

  • Akira Shiono & Jiro Kogo & Hiroki Sasaki & Ryo Yomoda & Tatsuya Jujo & Naoto Tokuda & Yasushi Kitaoka & Hitoshi Takagi, 2018. "Optical coherence tomography findings as a predictor of clinical course in patients with branch retinal vein occlusion treated with ranibizumab," PLOS ONE, Public Library of Science, vol. 13(6), pages 1-15, June.
    • Handle: RePEc:plo:pone00:0199552
    DOI: 10.1371/journal.pone.0199552
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