IDEAS home Printed from https://ideas.repec.org/a/plo/pone00/0199157.html
   My bibliography  Save this article

Classification of primary angle closure spectrum with hierarchical cluster analysis

Author

Listed:
  • Sasan Moghimi
  • Ali Torkashvand
  • Massood Mohammadi
  • Mehdi Yaseri
  • Luke J Saunders
  • Shan C Lin
  • Robert N Weinreb

Abstract

Purpose: To classify subjects with primary angle closure into clusters based on features from anterior segment optical coherence tomography (ASOCT) imaging and to explore how these clusters correspond to disease subtypes, including primary angle closure suspect (PACS), primary angle closure glaucoma(PACG), acute primary angle closure (APAC) and fellow eyes of APAC and reveal the factors that become more predominant in each subtype of angle closure. Method: A cross-sectional study of 248 eyes of 198 subjects(88 PACS eyes, 53 PACG eyes, 54 APAC eyes and 53 fellow eyes of APAC) that underwent complete examination including gonioscopy, A-scan biometry, and ASOCT. An agglomerative hierarchical clustering method was used to classify eyes based on ASOCT parameters. Results: Statistical clustering analysis produced three clusters among which the anterior segment parameters were significantly different. Cluster 1(43 eyes) had the smallest anterior chamber depth(ACD) and area, as well as the greatest lens vault (p

Suggested Citation

  • Sasan Moghimi & Ali Torkashvand & Massood Mohammadi & Mehdi Yaseri & Luke J Saunders & Shan C Lin & Robert N Weinreb, 2018. "Classification of primary angle closure spectrum with hierarchical cluster analysis," PLOS ONE, Public Library of Science, vol. 13(7), pages 1-14, July.
    • Handle: RePEc:plo:pone00:0199157
    DOI: 10.1371/journal.pone.0199157
    as

    Download full text from publisher

    File URL: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0199157
    Download Restriction: no
    File URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0199157&type=printable
    Download Restriction: no
    File URL: https://libkey.io/10.1371/journal.pone.0199157?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:plo:pone00:0199157. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: plosone (email available below). General contact details of provider: https://journals.plos.org/plosone/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.