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Creatine kinase is associated with reduced inflammation in a general population: The Tromsø study

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  • Svein Ivar Bekkelund
  • Stein Harald Johnsen

Abstract

Background: Creatine kinase (CK) has been associated with reduced inflammation in obesity while inflammation is associated with obesity-related cardiovascular diseases. We investigated the relationship between CK and high sensitive C-reactive protein (hs-CRP) in a general population. Methods: CK and hs-CRP were measured in the population-based Tromsø study that included entire birth cohorts and random samples of citizens between 30–87 years of age. The analyses were performed sex-stratified in 5969 men and 6827 women. Results: CK correlated negatively with hs-CRP in men (r = -0.08, P

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  • Svein Ivar Bekkelund & Stein Harald Johnsen, 2018. "Creatine kinase is associated with reduced inflammation in a general population: The Tromsø study," PLOS ONE, Public Library of Science, vol. 13(5), pages 1-11, May.
    • Handle: RePEc:plo:pone00:0198133
    DOI: 10.1371/journal.pone.0198133
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