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Effect of maternal age on the risk of preterm birth: A large cohort study

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  • Florent Fuchs
  • Barbara Monet
  • Thierry Ducruet
  • Nils Chaillet
  • Francois Audibert

Abstract

Background: Maternal age at pregnancy is increasing worldwide as well as preterm birth. However, the association between prematurity and advanced maternal age remains controversial. Objective: To evaluate the impact of maternal age on the occurrence of preterm birth after controlling for multiple known confounders in a large birth cohort. Study design: Retrospective cohort study using data from the QUARISMA study, a large Canadian randomized controlled trial, which collected data from 184,000 births in 32 hospitals. Inclusion criteria were maternal age over 20 years. Exclusion criteria were multiple pregnancy, fetal malformation and intra-uterine fetal death. Five maternal age categories were defined and compared for maternal characteristics, gestational and obstetric complications, and risk factors for prematurity. Risk factors for preterm birth

Suggested Citation

  • Florent Fuchs & Barbara Monet & Thierry Ducruet & Nils Chaillet & Francois Audibert, 2018. "Effect of maternal age on the risk of preterm birth: A large cohort study," PLOS ONE, Public Library of Science, vol. 13(1), pages 1-10, January.
    • Handle: RePEc:plo:pone00:0191002
    DOI: 10.1371/journal.pone.0191002
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