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Hospitalization and medical cost of patients with elevated serum N-terminal pro-brain natriuretic peptide levels

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  • Toshiro Kitagawa
  • Noboru Oda
  • Mariko Mizukawa
  • Takayuki Hidaka
  • Makiko Naka
  • Susumu Nakayama
  • Yasuki Kihara

Abstract

Background: Patients with heart failure (HF) are reportedly at high risk for ‘all-cause’ re-hospitalization. A biomarker for HF, N-terminal pro-brain natriuretic peptide (NT-proBNP), enables to simply detect patients with possible HF (pHF). We examined the hospitalization and medical cost of Japanese patients detected by an elevated serum NT-proBNP, and also evaluated the effects of institutional team approaches for HF on their all-cause hospitalizations. Methods: We retrospectively extracted all adult patients with serum NT-proBNP ≥400 pg/ml measured between January and March 2012 in Hiroshima University Hospital as pHF-positive patients. We studied their all-cause hospitalization records during the past 3-year period. We also extracted all pHF-negative patients with NT-proBNP

Suggested Citation

  • Toshiro Kitagawa & Noboru Oda & Mariko Mizukawa & Takayuki Hidaka & Makiko Naka & Susumu Nakayama & Yasuki Kihara, 2018. "Hospitalization and medical cost of patients with elevated serum N-terminal pro-brain natriuretic peptide levels," PLOS ONE, Public Library of Science, vol. 13(1), pages 1-12, January.
    • Handle: RePEc:plo:pone00:0190979
    DOI: 10.1371/journal.pone.0190979
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