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The Berkeley Dry Eye Flow Chart: A fast, functional screening instrument for contact lens-induced dryness

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  • Andrew D Graham
  • Erika L Lundgrin
  • Meng C Lin

Abstract

Purpose: In this article, we introduce a novel flow chart-based screening tool for the categorization of contact lens-induced dryness (CLIDE) and its impact on daily visual activities: the Berkeley Dry Eye Flow Chart (DEFC). Methods: One hundred thirty (130) experienced soft contact lens wearers discontinued lens wear for 24 hrs, passed a baseline screening and eye health examination, completed the Ocular Surface Disease Index (OSDI) then were dispensed fresh pairs of their habitual lenses. After 6 hrs of wear, subjects were administered a battery of symptom questionnaires, and underwent non–invasive tear breakup time (NITBUT) measurement, grading of distortion in reflected topographer mires, grading of lens surface wettability, and a fluorescein examination of the ocular surface. Subjects returned after at least 48 hrs and repeated all assessments after 6 hrs of wear of a second fresh pair of habitual lenses. Results: The repeatability of the DEFC between visits was within 1%, and Limits of Agreement and Coefficient of Repeatability were comparable to those of the other CLIDE assessments. Higher DEFC score was significantly related to shorter pre-lens NITBUT, higher OSDI score, and higher Visual Analog Scale (VAS) ratings of average and end-of-day severity and frequency of dryness (all p

Suggested Citation

  • Andrew D Graham & Erika L Lundgrin & Meng C Lin, 2018. "The Berkeley Dry Eye Flow Chart: A fast, functional screening instrument for contact lens-induced dryness," PLOS ONE, Public Library of Science, vol. 13(1), pages 1-18, January.
    • Handle: RePEc:plo:pone00:0190752
    DOI: 10.1371/journal.pone.0190752
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