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The safety and efficacy of hybrid ablation for the treatment of atrial fibrillation: A meta-analysis

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Listed:
  • Yun-Qiu Jiang
  • Ying Tian
  • Li-Jun Zeng
  • Shu-Nan He
  • Zhi-Tao Zheng
  • Liang Shi
  • Yan-Jiang Wang
  • Yu-Xing Wang
  • Xian-Dong Yin
  • Xiao-Qing Liu
  • Xin-Chun Yang
  • Xing-Peng Liu

Abstract

Introduction: Hybrid ablation, an emerging therapy that combines surgical intervention and catheter ablation, has become a viable option for the treatment of persistent atrial fibrillation. In this analysis, we aimed to evaluate the safety and efficacy of hybrid ablation, as well as compare the outcomes of one-step and staged approaches. Methods: We conducted a search in major online databases and selected the studies that met the inclusion criteria. The primary endpoint was defined as no episode of atrial fibrillation or atrial tachycardia lasting longer than 30 seconds without administration of antiarrhythmic drugs. Results: Sixteen studies including 785 patients (paroxysmal atrial fibrillation, n = 83; persistent atrial fibrillation, n = 214; long-standing persistent atrial fibrillation, n = 488) were selected. Average history of atrial fibrillation was (5.0±1.6) years. The pooled proportion of patients who were arrhythmia-free at the primary endpoint was 73% (95% CI, 64%–81%, Cochran’s Q, P

Suggested Citation

  • Yun-Qiu Jiang & Ying Tian & Li-Jun Zeng & Shu-Nan He & Zhi-Tao Zheng & Liang Shi & Yan-Jiang Wang & Yu-Xing Wang & Xian-Dong Yin & Xiao-Qing Liu & Xin-Chun Yang & Xing-Peng Liu, 2018. "The safety and efficacy of hybrid ablation for the treatment of atrial fibrillation: A meta-analysis," PLOS ONE, Public Library of Science, vol. 13(1), pages 1-16, January.
    • Handle: RePEc:plo:pone00:0190170
    DOI: 10.1371/journal.pone.0190170
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