IDEAS home Printed from https://ideas.repec.org/a/plo/pone00/0189045.html
   My bibliography  Save this article

Proportion and factors associated with recent HIV infection in a cohort of patients seen for care in Italy over 1996-2014: Data from the ICONA Foundation Study cohort

Author

Listed:
  • Silvia Nozza
  • Alessandro Cozzi-Lepri
  • Francesca Bai
  • Stefano Rusconi
  • Andrea Gori
  • Paola Cinque
  • Adriana Ammassari
  • Pietro Caramello
  • Giuseppe Tambussi
  • Antonella D’Arminio Monforte
  • Giulia Marchetti
  • on behalf of Icona Foundation Study Group

Abstract

In Italy the prevalence of recent HIV infection (RHI) isn’t currently monitored. Early diagnosis is crucial to allow introduction of antiretroviral therapy (cART) in the recent phase of infection. We aimed to estimate the proportion and the determinants of RHI among patients enrolled in the ICONA cohort; we explored differences in the median time from HIV diagnosis to cART initiation and in the viro-immunological response between RHI and Less Recent HIV infections (NRHI). We included antiretroviral-naïve HIV-positive patients enrolled in the cohort with documented dates of HIV-negative and positive antibodies tests, grouped in RHI (estimated date of seroconversion within 12 months of enrolment) and NRHI. Proportion of RHI and the trend of this proportion by calendar period (1996–2014) were investigated (Chi-square test). Logistic regression analysis was employed to identify factors associated with RHI. The time from seroconversion to cART initiation was compared in RHI and NRHI overall and after stratification by calendar period (survival analysis). We finally explored the time from starting cART to HIV-RNA

Suggested Citation

  • Silvia Nozza & Alessandro Cozzi-Lepri & Francesca Bai & Stefano Rusconi & Andrea Gori & Paola Cinque & Adriana Ammassari & Pietro Caramello & Giuseppe Tambussi & Antonella D’Arminio Monforte & Giulia , 2017. "Proportion and factors associated with recent HIV infection in a cohort of patients seen for care in Italy over 1996-2014: Data from the ICONA Foundation Study cohort," PLOS ONE, Public Library of Science, vol. 12(12), pages 1-16, December.
    • Handle: RePEc:plo:pone00:0189045
    DOI: 10.1371/journal.pone.0189045
    as

    Download full text from publisher

    File URL: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0189045
    Download Restriction: no
    File URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0189045&type=printable
    Download Restriction: no
    File URL: https://libkey.io/10.1371/journal.pone.0189045?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:plo:pone00:0189045. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: plosone (email available below). General contact details of provider: https://journals.plos.org/plosone/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.