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A machine learning approach to triaging patients with chronic obstructive pulmonary disease

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Listed:
  • Sumanth Swaminathan
  • Klajdi Qirko
  • Ted Smith
  • Ethan Corcoran
  • Nicholas G Wysham
  • Gaurav Bazaz
  • George Kappel
  • Anthony N Gerber

Abstract

COPD patients are burdened with a daily risk of acute exacerbation and loss of control, which could be mitigated by effective, on-demand decision support tools. In this study, we present a machine learning-based strategy for early detection of exacerbations and subsequent triage. Our application uses physician opinion in a statistically and clinically comprehensive set of patient cases to train a supervised prediction algorithm. The accuracy of the model is assessed against a panel of physicians each triaging identical cases in a representative patient validation set. Our results show that algorithm accuracy and safety indicators surpass all individual pulmonologists in both identifying exacerbations and predicting the consensus triage in a 101 case validation set. The algorithm is also the top performer in sensitivity, specificity, and ppv when predicting a patient’s need for emergency care.

Suggested Citation

  • Sumanth Swaminathan & Klajdi Qirko & Ted Smith & Ethan Corcoran & Nicholas G Wysham & Gaurav Bazaz & George Kappel & Anthony N Gerber, 2017. "A machine learning approach to triaging patients with chronic obstructive pulmonary disease," PLOS ONE, Public Library of Science, vol. 12(11), pages 1-21, November.
  • Handle: RePEc:plo:pone00:0188532
    DOI: 10.1371/journal.pone.0188532
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    Cited by:

    1. Douglas Spangler & Thomas Hermansson & David Smekal & Hans Blomberg, 2019. "A validation of machine learning-based risk scores in the prehospital setting," PLOS ONE, Public Library of Science, vol. 14(12), pages 1-18, December.
    2. Adam Ceney & Stephanie Tolond & Andrzej Glowinski & Ben Marks & Simon Swift & Tom Palser, 2021. "Accuracy of online symptom checkers and the potential impact on service utilisation," PLOS ONE, Public Library of Science, vol. 16(7), pages 1-16, July.

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