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Long-term prognostic factors of chronic central serous chorioretinopathy after half-dose photodynamic therapy: A 3-year follow-up study

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  • Fuminori Haga
  • Ruka Maruko
  • Chiaki Sato
  • Keiko Kataoka
  • Yasuki Ito
  • Hiroko Terasaki

Abstract

Purpose: To evaluate the long-term efficacy and factors involved in the recurrence and persistence of subretinal fluid (SRF) after half-dose photodynamic therapy (PDT) for chronic central serous chorioretinopathy (CSC). Methods: In this retrospective observational case series, 79 eyes (73 patients) with chronic CSC were treated with half-dose PDT and followed up for at least 3 years. They were divided into successful (64 eyes) and unsuccessful (15 eyes) groups based on SRF absorption and disease recurrence after one PDT session. Age, best-corrected visual acuity (BCVA), central foveal thickness, neuroretinal thickness, height of SRF, subfoveal choroidal thickness, window defect area detected by fluorescein angiography, and PDT spot area were compared between the groups. Factors associated with PDT success and BCVA at 3 years were investigated. Results: LogMAR BCVA improved from 0.21±0.24 to 0.08±0.16 (P

Suggested Citation

  • Fuminori Haga & Ruka Maruko & Chiaki Sato & Keiko Kataoka & Yasuki Ito & Hiroko Terasaki, 2017. "Long-term prognostic factors of chronic central serous chorioretinopathy after half-dose photodynamic therapy: A 3-year follow-up study," PLOS ONE, Public Library of Science, vol. 12(7), pages 1-11, July.
    • Handle: RePEc:plo:pone00:0181479
    DOI: 10.1371/journal.pone.0181479
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