IDEAS home Printed from https://ideas.repec.org/a/plo/pone00/0179914.html
   My bibliography  Save this article

Use of fecal volatile organic compound analysis to discriminate between non-vaccinated and BCG—Vaccinated cattle prior to and after Mycobacterium bovis challenge

Author

Listed:
  • Christine K Ellis
  • Somchai Rice
  • Devin Maurer
  • Randal Stahl
  • W Ray Waters
  • Mitchell V Palmer
  • Pauline Nol
  • Jack C Rhyan
  • Kurt C VerCauteren
  • Jacek A Koziel

Abstract

Bovine tuberculosis is a zoonotic disease of global public health concern. Development of diagnostic tools to improve test accuracy and efficiency in domestic livestock and enable surveillance of wildlife reservoirs would improve disease management and eradication efforts. Use of volatile organic compound analysis in breath and fecal samples is being developed and optimized as a means to detect disease in humans and animals. In this study we demonstrate that VOCs present in fecal samples can be used to discriminate between non-vaccinated and BCG-vaccinated cattle prior to and after Mycobacterium bovis challenge.

Suggested Citation

  • Christine K Ellis & Somchai Rice & Devin Maurer & Randal Stahl & W Ray Waters & Mitchell V Palmer & Pauline Nol & Jack C Rhyan & Kurt C VerCauteren & Jacek A Koziel, 2017. "Use of fecal volatile organic compound analysis to discriminate between non-vaccinated and BCG—Vaccinated cattle prior to and after Mycobacterium bovis challenge," PLOS ONE, Public Library of Science, vol. 12(7), pages 1-25, July.
    • Handle: RePEc:plo:pone00:0179914
    DOI: 10.1371/journal.pone.0179914
    as

    Download full text from publisher

    File URL: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0179914
    Download Restriction: no
    File URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0179914&type=printable
    Download Restriction: no
    File URL: https://libkey.io/10.1371/journal.pone.0179914?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    References listed on IDEAS

    as
    1. O. Carrión & A. R. J. Curson & D. Kumaresan & Y. Fu & A. S. Lang & E. Mercadé & J. D. Todd, 2015. "A novel pathway producing dimethylsulphide in bacteria is widespread in soil environments," Nature Communications, Nature, vol. 6(1), pages 1-8, May.
    2. Christine K Ellis & Randal S Stahl & Pauline Nol & W Ray Waters & Mitchell V Palmer & Jack C Rhyan & Kurt C VerCauteren & Matthew McCollum & M D Salman, 2014. "A Pilot Study Exploring the Use of Breath Analysis to Differentiate Healthy Cattle from Cattle Experimentally Infected with Mycobacterium bovis," PLOS ONE, Public Library of Science, vol. 9(2), pages 1-12, February.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.

      More about this item

      Statistics

      Access and download statistics

      Corrections

      All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:plo:pone00:0179914. See general information about how to correct material in RePEc.

      If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

      If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

      If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

      For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: plosone (email available below). General contact details of provider: https://journals.plos.org/plosone/ .

      Please note that corrections may take a couple of weeks to filter through the various RePEc services.

      IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.