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Impact of Sjogren's syndrome on Parkinson’s disease: A nationwide case-control study

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Listed:
  • Ming-Chi Wu
  • Xun Xu
  • Shan-Ming Chen
  • Yeu-Sheng Tyan
  • Jeng-Yuan Chiou
  • Yu-Hsun Wang
  • Li-Chi Lin
  • Chyong-Mei Chen
  • James Cheng-Chung Wei

Abstract

Objective: To investigate whether Sjogren’s syndrome would have an influence on the development of Parkinson’s disease. Methods: A population-based case-control study was conducted. Participants consisted of 7716 subjects with newly diagnosed Parkinson’s disease and a population of 75129 matched control subjects between 2000 and 2010. We measured the risk of Parkinson’s disease in association with Sjogren’s syndrome by using adjusted odds ratios. Results: A total of 143 Parkinson’s disease subjects (1.9%) and 893 control subjects (1.2%) suffered from Sjogren’s syndrome (p

Suggested Citation

  • Ming-Chi Wu & Xun Xu & Shan-Ming Chen & Yeu-Sheng Tyan & Jeng-Yuan Chiou & Yu-Hsun Wang & Li-Chi Lin & Chyong-Mei Chen & James Cheng-Chung Wei, 2017. "Impact of Sjogren's syndrome on Parkinson’s disease: A nationwide case-control study," PLOS ONE, Public Library of Science, vol. 12(7), pages 1-10, July.
  • Handle: RePEc:plo:pone00:0175836
    DOI: 10.1371/journal.pone.0175836
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