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Procalcitonin for selecting the antibiotic regimen in outpatients with low-risk community-acquired pneumonia using a rapid point-of-care testing: A single-arm clinical trial

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  • Mar Masiá
  • Sergio Padilla
  • Victoria Ortiz de la Tabla
  • Matilde González
  • Cristina Bas
  • Félix Gutiérrez

Abstract

Objective: We aimed to assess the role of procalcitonin (PCT) to guide the initial selection of the antibiotic regimen for low-risk community-acquired pneumonia (CAP). Methods: A single-arm clinical trial was conducted including outpatients with CAP and Pneumonia Severity Index risk classes I-II. Antimicrobial selection was based on the results of PCT measured with a rapid point-of-care testing. According to serum PCT levels, patients were assigned to two treatment strategies: oral azithromycin if PCT was

Suggested Citation

  • Mar Masiá & Sergio Padilla & Victoria Ortiz de la Tabla & Matilde González & Cristina Bas & Félix Gutiérrez, 2017. "Procalcitonin for selecting the antibiotic regimen in outpatients with low-risk community-acquired pneumonia using a rapid point-of-care testing: A single-arm clinical trial," PLOS ONE, Public Library of Science, vol. 12(4), pages 1-12, April.
  • Handle: RePEc:plo:pone00:0175634
    DOI: 10.1371/journal.pone.0175634
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