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The impact of atosiban on pregnancy outcomes in women undergoing in vitro fertilization-embryo transfer: A meta-analysis

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  • Qian-Yi Huang
  • Min-Hua Rong
  • Ai-Hua Lan
  • Xiao-Miao Lin
  • Xing-Gu Lin
  • Rong-Quan He
  • Gang Chen
  • Mu-Jun Li

Abstract

Background: Atosiban is administered to women undergoing in vitro fertilization-embryo transfer (IVF-ET) to improve pregnancy outcomes. However, the results of this treatment were controversial. We conducted this meta-analysis to investigate whether atosiban improves pregnancy outcomes in the women undergoing in vitro fertilization (IVF). Methods: Databases of PubMed, EMBASE, Web of Science, China BioMedicine, and Google Scholar were systematically searched. Meta-analyses were performed to investigate whether atosiban improves pregnancy outcomes in the women undergoing IVF. Results: Our results showed that atosiban was associated with higher implantation (OR = 1.63, 95% CI: 1.17–2.27; P = 0.004) and clinical pregnancy (OR = 1.84, 95% CI: 1.31–2.57; P

Suggested Citation

  • Qian-Yi Huang & Min-Hua Rong & Ai-Hua Lan & Xiao-Miao Lin & Xing-Gu Lin & Rong-Quan He & Gang Chen & Mu-Jun Li, 2017. "The impact of atosiban on pregnancy outcomes in women undergoing in vitro fertilization-embryo transfer: A meta-analysis," PLOS ONE, Public Library of Science, vol. 12(4), pages 1-15, April.
    • Handle: RePEc:plo:pone00:0175501
    DOI: 10.1371/journal.pone.0175501
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