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Screening gestational diabetes mellitus: The role of maternal age

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Listed:
  • Chun-Heng Kuo
  • Szu-Chi Chen
  • Chi-Tai Fang
  • Feng-Jung Nien
  • En-Tzu Wu
  • Shin-Yu Lin
  • Lee-Ming Chuang
  • Chien-Nan Lee
  • Hung-Yuan Li

Abstract

Objective: Using a specific cutoff of fasting plasma glucose (FPG) to screen gestational diabetes mellitus (GDM) can reduce the use of oral glucose tolerance tests (OGTT). Since the prevalence of GDM increases with age, this screening method may not be appropriate in healthcare systems where women become pregnant at older ages. Therefore, we aimed to develop a screening algorithm for GDM that takes maternal age into consideration. Methods: We included 945 pregnant women without history of GDM who received 75g OGTT to diagnose GDM in 2011. Screening algorithms using FPG with or without age were developed. Another 362 pregnant women were recruited in 2013–2015 as the validation cohort. Results: Using FPG criteria alone, more GDM diagnoses were missed in women ≥35 years than in women

Suggested Citation

  • Chun-Heng Kuo & Szu-Chi Chen & Chi-Tai Fang & Feng-Jung Nien & En-Tzu Wu & Shin-Yu Lin & Lee-Ming Chuang & Chien-Nan Lee & Hung-Yuan Li, 2017. "Screening gestational diabetes mellitus: The role of maternal age," PLOS ONE, Public Library of Science, vol. 12(3), pages 1-13, March.
    • Handle: RePEc:plo:pone00:0173049
    DOI: 10.1371/journal.pone.0173049
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    Cited by:

    1. Samira Behboudi-Gandevani & Ranjan Parajuli & Mojtaba Vaismoradi, 2021. "A Systematic Review of the Prevalence of Gestational Diabetes in Norway," IJERPH, MDPI, vol. 18(4), pages 1-11, February.
    2. Yi-Yun Tai & Chien-Nan Lee & Chun-Heng Kuo & Ming-Wei Lin & Kuan-Yu Chen & Shin-Yu Lin & Hung-Yuan Li, 2020. "Simplifying the screening of gestational diabetes by maternal age plus fasting plasma glucose at first prenatal visit: A prospective cohort study," PLOS ONE, Public Library of Science, vol. 15(8), pages 1-12, August.

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