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Prevalence of ESBL-Producing Enterobacteriaceae in Pediatric Bloodstream Infections: A Systematic Review and Meta-Analysis

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  • Myrto Eleni Flokas
  • Styliani Karanika
  • Michail Alevizakos
  • Eleftherios Mylonakis

Abstract

Background: Pediatric bloodstream infections (BSIs) with Extended-Spectrum Beta-Lactamase- producing Enterobacteriaceae (ESBL-PE) are associated with worse clinical outcomes. We aimed to estimate the prevalence of and the mortality associated with ESBL-PE in this patient population. Methods: A systematic review and meta-analysis using PubMed and EMBASE and included studies reporting the prevalence of ESBL-PE among confirmed BSIs in patients

Suggested Citation

  • Myrto Eleni Flokas & Styliani Karanika & Michail Alevizakos & Eleftherios Mylonakis, 2017. "Prevalence of ESBL-Producing Enterobacteriaceae in Pediatric Bloodstream Infections: A Systematic Review and Meta-Analysis," PLOS ONE, Public Library of Science, vol. 12(1), pages 1-13, January.
    • Handle: RePEc:plo:pone00:0171216
    DOI: 10.1371/journal.pone.0171216
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    1. Awa Ndir & Amadou Diop & Pape Makhtar Faye & Moussa Fafa Cissé & Babacar Ndoye & Pascal Astagneau, 2016. "Epidemiology and Burden of Bloodstream Infections Caused by Extended-Spectrum Beta-Lactamase Producing Enterobacteriaceae in a Pediatric Hospital in Senegal," PLOS ONE, Public Library of Science, vol. 11(2), pages 1-13, February.
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