IDEAS home Printed from https://ideas.repec.org/a/plo/pone00/0169311.html
   My bibliography  Save this article

Prediction of Small for Gestational Age Infants in Healthy Nulliparous Women Using Clinical and Ultrasound Risk Factors Combined with Early Pregnancy Biomarkers

Author

Listed:
  • Lesley M E McCowan
  • John M D Thompson
  • Rennae S Taylor
  • Philip N Baker
  • Robyn A North
  • Lucilla Poston
  • Claire T Roberts
  • Nigel A B Simpson
  • James J Walker
  • Jenny Myers
  • Louise C Kenny
  • On behalf of the SCOPE consortium

Abstract

Objective: Most small for gestational age pregnancies are unrecognised before birth, resulting in substantial avoidable perinatal mortality and morbidity. Our objective was to develop multivariable prediction models for small for gestational age combining clinical risk factors and biomarkers at 15±1 weeks’ with ultrasound parameters at 20±1 weeks’ gestation. Methods: Data from 5606 participants in the Screening for Pregnancy Endpoints (SCOPE) cohort study were divided into Training (n = 3735) and Validation datasets (n = 1871). The primary outcomes were All-SGA (small for gestational age with birthweight

Suggested Citation

  • Lesley M E McCowan & John M D Thompson & Rennae S Taylor & Philip N Baker & Robyn A North & Lucilla Poston & Claire T Roberts & Nigel A B Simpson & James J Walker & Jenny Myers & Louise C Kenny & On b, 2017. "Prediction of Small for Gestational Age Infants in Healthy Nulliparous Women Using Clinical and Ultrasound Risk Factors Combined with Early Pregnancy Biomarkers," PLOS ONE, Public Library of Science, vol. 12(1), pages 1-15, January.
    • Handle: RePEc:plo:pone00:0169311
    DOI: 10.1371/journal.pone.0169311
    as

    Download full text from publisher

    File URL: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0169311
    Download Restriction: no
    File URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0169311&type=printable
    Download Restriction: no
    File URL: https://libkey.io/10.1371/journal.pone.0169311?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:plo:pone00:0169311. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: plosone (email available below). General contact details of provider: https://journals.plos.org/plosone/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.