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Subfoveal Choroidal Thickness in Central Serous Chorioretinopathy: A Meta-Analysis

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  • Guohai Chen
  • Radouil Tzekov
  • Wensheng Li
  • Fangzheng Jiang
  • Sihong Mao
  • Yuhua Tong

Abstract

Purpose: To evaluate the relationship between subfoveal choroidal thickness (SFCT) and eyes with central serous chorioretinopathy (CSC) versus fellow or control eyes. Methods: We performed a meta-analysis using databases including PubMed, Embase and ISI Web of Science to find relevant studies. Weighted mean difference (WMD) was calculated for the SFCT in CSC eyes, the unaffected fellow eyes and normal controls. Results: Twelve studies were selected for this meta-analysis, including 1108 eyes (397 CSC eyes, 228 unaffected fellow eyes and 483 eyes of normal controls). The meta-analysis clearly demonstrated that the subfoveal choiroid of eyes with a clinical presentation of CSC was thickened compared to unaffected fellow eyes (WMD = 52.81, 95% confidence interval (CI), 39.13–66.49, P

Suggested Citation

  • Guohai Chen & Radouil Tzekov & Wensheng Li & Fangzheng Jiang & Sihong Mao & Yuhua Tong, 2017. "Subfoveal Choroidal Thickness in Central Serous Chorioretinopathy: A Meta-Analysis," PLOS ONE, Public Library of Science, vol. 12(1), pages 1-13, January.
    • Handle: RePEc:plo:pone00:0169152
    DOI: 10.1371/journal.pone.0169152
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